abstract：CONCLUSIONS:Local administration of MP delivered by the C/GP-MP-hydrogel can improve the recovery of facial nerve following crush injury. The findings suggested that locally injected MP delivered by C/GP-hydrogel might be a promising treatment for facial nerve damage. OBJECTIVES:In this study, the aim is to assess the...

journal_title：Acta oto-laryngologica

authors： Chao X,Fan Z,Han Y,Wang Y,Li J,Chai R,Xu L,Wang H

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:Idiopathic otolithic vertigo (IOV) with relatively long duration of attacks might be caused by endolymphatic hydrops in the otolith organ. OBJECTIVES:To clarify the pathophysiology underlying IOV, episodic tilting or translational sensation attacks by unknown causes, especially the possibility of endolympha...

journal_title：Acta oto-laryngologica

authors： Murofushi T,Komiyama S,Hayashi Y,Yoshimura E

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:Salivary stones in the parotid gland that are not amenable to endoscopic extraction can safely be removed by a combined, endoscopic-external approach. OBJECTIVE:Limitations for endoscopic removability of salivary stones from the parotid gland are immobile stones in the deeper salivary duct system. A combine...

journal_title：Acta oto-laryngologica

authors： Mikolajczak S,Bremke M,Beutner D,Luers JC

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:Endoscopic surgery improved facial pain/headache and physical-psychosocial impacts in patients with nasal polyposis. However, one fifth of patients still experienced residual pain after surgery, requiring neurologic counseling to look for the non-sinonasal cause of their symptoms. OBJECTIVE:Considering the ...

journal_title：Acta oto-laryngologica

authors： Nguyen DT,Felix-Ravelo M,Arous F,Nguyen-Thi PL,Jankowski R

更新日期：2015-01-01 00:00:00

abstract：CONCLUSION:A man-made bone tunnel of 1.5 turns around the modiolus can be created in cases of total cochlear ossification. Patients with ossified cochlea types I and II achieved satisfactory hearing results after cochlear implantation (CI). Patients with ossified cochlea type III, in which the modiolus is damaged by th...

journal_title：Acta oto-laryngologica

authors： Wang L,Zhang D

更新日期：2014-12-01 00:00:00

abstract：CONCLUSION:In the present study, about one-third of patients with Meniere's disease developed benign paroxysmal positional vertigo (BPPV)-like attacks. Additionally, more than one-third of all vertigo attacks were BPPV-like attacks. Thus, vertigo attacks in patients with Meniere's disease must be carefully treated beca...

journal_title：Acta oto-laryngologica

authors： Taura A,Funabiki K,Ohgita H,Ogino E,Torii H,Matsunaga M,Ito J

更新日期：2014-11-01 00:00:00

abstract：CONCLUSION:This study suggests that hyperbilirubinemia in the neonatal rat can impair auditory function and induce peripheral nerve pathology by reducing neurofilament-positive cells in spiral ganglion neurons (SGNs). This finding indicates a potential connection between hyperbilirubinemia and auditory impairment. OBJ...

journal_title：Acta oto-laryngologica

authors： Li Q,Chen P,Guo W,Fang R,Yang S

更新日期：2014-11-01 00:00:00

abstract：CONCLUSION:Concomitant antiemetic therapy comprising fosaprepitant, palonosetron, and dexamethasone is effective for head and neck carcinoma. OBJECTIVE:A patient diary was constructed to determine the effectiveness of concomitant antiemetic therapy with a neurokinin-1 receptor antagonist (fosaprepitant), 5-hydroxytryp...

journal_title：Acta oto-laryngologica

authors： Tsukahara K,Nakamura K,Motohashi R,Sato H,Endo M,Katsube Y,Ueda Y,Suzuki M

更新日期：2014-11-01 00:00:00

abstract：CONCLUSION:Neck dissection (ND) may not be warranted for those patients with complete response in the neck. Human papillomavirus (HPV)-positive or -negative tumour does not affect this recommendation. OBJECTIVES:Treatment of tonsillar cancer varies considerably worldwide, although non-surgical treatment, e.g. radiothe...

journal_title：Acta oto-laryngologica

authors： Marklund L,Lundberg B,Hammarstedt-Nordenvall L

更新日期：2014-10-01 00:00:00

abstract：CONCLUSIONS:Surgery for oral or oropharyngeal cancer with free-flap reconstruction is associated with moderate but persistent functional and quality of life (QoL) problems. Patient age, tumor stage, tumor site, and radiotherapy were the main predictors of functional outcome. OBJECTIVES:To evaluate long-term functional...

journal_title：Acta oto-laryngologica

authors： Pierre CS,Dassonville O,Chamorey E,Poissonnet G,Riss JC,Ettaiche M,Peyrade F,Benezery K,Chand ME,Leyssalle A,Sudaka A,Haudebourg J,Santini J,Bozec A

更新日期：2014-10-01 00:00:00

abstract：CONCLUSIONS:Increased expression of Dicer may be a prognostic biomarker for patients with laryngeal squamous cell carcinoma (LSCC). OBJECTIVES:Recent studies have shown that many microRNAs (miRNAs) play an important role in the development and progression of human cancers. Dicer, one of the most important enzymes of t...

journal_title：Acta oto-laryngologica

authors： Gao C,Li X,Tong B,Wu K,Liu Y,Anniko M,Duan M

更新日期：2014-09-01 00:00:00

abstract：CONCLUSION:Photodynamic therapy (PDT) is a viable and safe option for early laryngeal cancer that would be less suitably treated with radiation or trans-oral laser surgery (TLS). The cure rates with PDT appear to be comparable to those of conventional therapy, and the voice outcomes are also comparable. In the case of ...

journal_title：Acta oto-laryngologica

authors： von Beckerath MP,Reizenstein JA,Berner AL,Nordqvist KW,Landström FJ,Löfgren AL,Möller CG

更新日期：2014-08-01 00:00:00

abstract：CONCLUSIONS:Over-adduction of the unaffected vocal fold may not compensate vocal function in unilateral vocal fold paralysis (UVFP). OBJECTIVE:To determine whether over-adduction of the unaffected vocal fold has any impact on vocal function in patients with UVFP. METHODS:A total of 101 patients with UVFP who underwen...

journal_title：Acta oto-laryngologica

authors： Yumoto E,Sanuki T,Minoda R,Kumai Y,Nishimoto K,Kodama N

更新日期：2014-07-01 00:00:00

abstract：CONCLUSION:The Finnish Matrix Test is the first sentence test in noise for the Finnish language. It was developed according to the HearCom standards and provides reliable speech intelligibility measurements with highly comparable results with the other international matrix tests. OBJECTIVES:The aim of the study was to...

journal_title：Acta oto-laryngologica

authors： Dietz A,Buschermöhle M,Aarnisalo AA,Vanhanen A,Hyyrynen T,Aaltonen O,Löppönen H,Zokoll MA,Kollmeier B

更新日期：2014-07-01 00:00:00

abstract：CONCLUSIONS:We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC mutation in the KCNQ4 gene. Families showing progressive high-frequency SNHL should be investigated for mutations in the KCNQ4 gene. OBJECTIVE:To determine the responsible deafness gene in a Japanese f...

journal_title：Acta oto-laryngologica

authors： Ishikawa K,Naito T,Nishio SY,Iwasa Y,Nakamura K,Usami S,Ichimura K

更新日期：2014-06-01 00:00:00

abstract：CONCLUSION:PET-CT scans seem to be sufficient to rule out residual tumour at the primary site. Patients with positive or equivocal PET findings should be scheduled for endoscopy with biopsy or a second PET-CT scan. OBJECTIVES:Assessment of remission at the primary site, in patients treated with organ preservation ther...

journal_title：Acta oto-laryngologica

authors： Sjövall J,Brun E,Almquist H,Kjellén E,Wahlberg P

更新日期：2014-06-01 00:00:00

abstract：CONCLUSIONS:Protocol limitations were identified and accounted for in the analysis. Percent gradient equilibrated (PGE) was affected by driving gradient direction in a similar manner to other efficiency measures. A finer resolution of possible age-related changes in eustachian tube opening efficiency is expected with t...

journal_title：Acta oto-laryngologica

authors： Swarts JD,Casselbrant ML,Teixeira MS,Mandel EM,Richert BC,Banks JM,El-Wagaa J,Doyle WJ

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze the safety and effectiveness of a new cochlear implant (CI) system developed in China, the Nurotron Venus device. MATERIAL AND METHODS:Fifteen post-lingually deafened patients received Nurotron Venus CIs in our hospital. The safety and effectiveness of the devices were ev...

journal_title：Acta oto-laryngologica

authors： Li J,Ji F,Chen W,Zhao H,Han D,Yang S

更新日期：2014-06-01 00:00:00

abstract：CONCLUSION:Human adipose-derived stem cells (ASCs), encapsulated in a fibrin-collagen hydrogel for the coating of an electrode array, produce sufficient amounts of neurotrophic factors and may be suitable for enhancing the bioelectric interface of cochlear implants (CIs). OBJECTIVES:To evaluate different hydrogel comp...

journal_title：Acta oto-laryngologica

authors： Schendzielorz P,Scherzed A,Rak K,Völker J,Hagen R,Mlynski R,Frölich K,Radeloff A

更新日期：2014-05-01 00:00:00

abstract：CONCLUSION:Our numerical simulation model provides an accurate reflection of nasal airflow, and the results were validated by clinical measurements. OBJECTIVES:To evaluate the accuracy of a numerical simulation model of nasal airflow. METHODS:Ten volunteers with normal nasal cavities underwent CT, acoustic rhinometry...

journal_title：Acta oto-laryngologica

authors： Lu J,Han D,Zhang L

更新日期：2014-05-01 00:00:00

abstract：CONCLUSIONS:Subtotal facial nerve decompression seems effective to prevent further episodes of facial palsy and promote facial nerve recovery for recurrent facial palsy in Melkersson Rosenthal syndrome (MRS). The main inflammatory sites of recurrent facial palsy in MRS may be the mastoid segment, tympanic segment, geni...

journal_title：Acta oto-laryngologica

authors： Dai C,Li J,Yang S,Zhao L,Feng S,Li Y,Song Z,Lu J,Zhao K

更新日期：2014-04-01 00:00:00

abstract：CONCLUSION:Patients with post-lingual deafness should not be excluded from cochlear implantation (CI) on the basis of duration of deafness. We found that the prognosis was favorable in patients who developed deafness after adolescence, even in those with extremely long-term deafness. OBJECTIVES:CI is an effective trea...

journal_title：Acta oto-laryngologica

authors： Moon IS,Park S,Kim HN,Lee WS,Kim SH,Kim JH,Choi JY

更新日期：2014-02-01 00:00:00

abstract：CONCLUSION:Vasomotor symptoms (VMS) and especially hot flushes are negatively associated with recovery from menopause-related dizziness. A further study is justified to determine whether hormone replacement therapy (HRT) can shorten this recovery time. OBJECTIVES:This study aimed to compare the rate of recovery from d...

journal_title：Acta oto-laryngologica

authors： Owada S,Suzuki M

更新日期：2014-02-01 00:00:00

abstract：CONCLUSION:The psychometric characteristics of Standard-Chinese lexical neighborhood test (LNT) confirmed the lexical effects of the four word categories. The established normative baseline can be used in evaluating the word-recognition performance of the hearing-impaired listeners. OBJECTIVES:The purpose of the prese...

journal_title：Acta oto-laryngologica

authors： Wang S,Liu S,Kong Y,Liu H,Feng J,Li S,Yang Y

更新日期：2014-01-01 00:00:00

abstract：CONCLUSION:Reconstruction with a vascularized bone flap provided superior postoperative outcomes compared with reconstruction with a soft tissue free flap. However, patients obtained acceptable long-term functional outcomes even with a soft tissue free flap and this method is an option in selected patients. A multidisc...

journal_title：Acta oto-laryngologica

authors： Mizukami T,Hyodo I,Fukamizu H,Mineta H

更新日期：2013-12-01 00:00:00

abstract：CONCLUSION:This study demonstrated that treatment with montelukast in combination with levocetirizine may have a beneficial effect on clinical improvement of middle ear fluid in children with otitis media with effusion (OME). OBJECTIVE:To evaluate the effect of the combination of montelukast and levocetirizine on shor...

journal_title：Acta oto-laryngologica

authors： Ertugay CK,Cingi C,Yaz A,San T,Ulusoy S,Erdogmus N,Ertugay OC

更新日期：2013-12-01 00:00:00

abstract：CONCLUSION:Early intervention may change the natural course of allergic rhinitis, preventing the progression to asthma. In particular, immunotherapy guarantees remission of local symptoms and valid protection against local and bronchial complications. Symptomatic treatment represents a valid alternative; it is always t...

journal_title：Acta oto-laryngologica

authors： Passali GC,Bellussi LM,De Corso E,Passali FM,Passali D

更新日期：2013-11-01 00:00:00

abstract：CONCLUSION:A 20 mm hole made backwards from the midpoint of the asterion to the mastoid process is suitable for a retrosigmoid keyhole approach with the aid of an endoscope. The endoscope-assisted retrosigmoid keyhole approach can be considered an effective and safe method for removal of vestibular schwannoma. OBJECTI...

journal_title：Acta oto-laryngologica

authors： Sun JQ,Sun JW

更新日期：2013-11-01 00:00:00

abstract：CONCLUSIONS:There was a moderate chance of cure after surgical salvage of recurrent hypopharyngeal squamous cell carcinoma (SCC). However, surgical salvage was only feasible for early recurrent tumor. Close follow-up surveillance to detect early recurrence is essential after primary treatment of patients. OBJECTIVES:D...

journal_title：Acta oto-laryngologica

authors： Yasumatsu R,Nakashima T,Toh S,Taura M,Komune S

更新日期：2013-10-01 00:00:00

abstract：CONCLUSION:Our results demonstrate for the first time a potentially enhanced basal secretion of monocyte chemoattractant protein-1 (MCP-1) and interleukin (IL)-17A-stimulated secretion of IL-6 from nasal polyp fibroblasts, enhanced basal secretion of IL-6 from eosinophilic nasal polyp fibroblasts, and a remarkable up-r...

journal_title：Acta oto-laryngologica

authors： Homma H,Kamiya K,Kusunoki T,Ikeda K

更新日期：2013-10-01 00:00:00

abstract：CONCLUSIONS:Endoscopic laser microsurgery (ELM) provides comparable oncological outcomes, and improved functional recovery and laryngeal preservation compared with open partial laryngopharyngectomy (OPLP) in patients with early squamous cell carcinoma of the hypopharynx (HPSCC). The use of open surgery is declining. Th...

journal_title：Acta oto-laryngologica

authors： Kuo CL,Lee TL,Chu PY

更新日期：2013-10-01 00:00:00

abstract：CONCLUSION:The necessity of considering cervical tuberculous lymphadenitis (CTL) should be emphasized even today for the differential diagnosis of cervical lymphadenopathy, particularly when it is located in the posterior triangle and supraclavicular regions even in patients without active pulmonary tuberculosis (PTB)....

journal_title：Acta oto-laryngologica

authors： Iguchi H,Wada T,Matsushita N,Teranishi Y,Yamane H

更新日期：2013-09-01 00:00:00

abstract：CONCLUSION:Endolymphatic hydrops could be a reversible inner ear pathological condition. After sac surgery, hydrops was reduced and symptoms went into remission in some cases, although vertigo suppression was not always a result of the reduced hydrops. OBJECTIVE:To examine the changes in endolymphatic hydrops detected...

journal_title：Acta oto-laryngologica

authors： Uno A,Imai T,Watanabe Y,Tanaka H,Kitahara T,Horii A,Kamakura T,Takimoto Y,Osaki Y,Nishiike S,Inohara H

更新日期：2013-09-01 00:00:00

abstract：CONCLUSION:Vestibular disturbance is frequent, but mild even immediately after stapes surgery. Vestibular symptoms improved or disappeared quickly, and they did not correlate with nystagmus. Outpatient stapes surgery performed under local anaesthesia is a feasible approach. OBJECTIVE:Vestibular symptoms are common and...

journal_title：Acta oto-laryngologica

authors： Hirvonen TP,Aalto H

更新日期：2013-08-01 00:00:00

abstract：CONCLUSION:Our results indicate that siRNA E6 and/or E7 may have potential as a gene-specific therapy for human papillomavirus (HPV) type 16 (HPV16)-related squamous cell carcinoma of the head and neck (HNSCC). OBJECTIVES:To evaluate the effectiveness of siRNA targeting E6 and/or E7 on the in vitro and in vivo growth ...

journal_title：Acta oto-laryngologica

authors： Adhim Z,Otsuki N,Kitamoto J,Morishita N,Kawabata M,Shirakawa T,Nibu K

更新日期：2013-07-01 00:00:00

abstract：CONCLUSION:The curative effect in the group where facial-facial anastomosis (FFA) was delayed for 7 days was similar to that in the immediate FFA group and had a better repair within 60 days. OBJECTIVE:Due to the uncertainty about optimal timing of delayed facial nerve repair, we designed an experimental study in guin...

journal_title：Acta oto-laryngologica

authors： Hu J,Zhou L,Ma Z

更新日期：2013-07-01 00:00:00

abstract：CONCLUSIONS:The procedure cleared the lesion completely and preserved the physiological function of the external auditory canal. OBJECTIVE:To develop a novel surgical procedure to treat chronic suppurative otitis media (CSOM). To explore the merit of using pedicled temporalis myofascia (PTM) and reconstruction of the ...

journal_title：Acta oto-laryngologica

authors： Yu F

更新日期：2013-07-01 00:00:00

abstract：CONCLUSION:Because nystagmus induced by ampullopetal inhibition of the posterior semicircular canal (PSCC) rotates around the axis perpendicular to the plane of the anterior semicircular canal (ASCC) of the other side, when free-floating debris is initially located at the distal portion of the PSCC, a patient showing p...

journal_title：Acta oto-laryngologica

authors： Imai T,Masumura C,Takeda N,Kitahara T,Uno A,Horii A,Nishiike S,Ohta Y,Shingai-Higashi K,Morihana T,Okazaki S,Kamakura T,Takimoto Y,Inohara H

更新日期：2013-06-01 00:00:00

abstract：CONCLUSIONS:The findings of this study demonstrated that the wait-and-watch strategy for neck metastasis from squamous cell carcinoma (SCC) of oral tongue is a reliable option and that salvage by surgical treatment is effective. However, younger patients should be closely monitored for recurrence. Adjuvant therapy may ...

journal_title：Acta oto-laryngologica

authors： Yuasa-Nakagawa K,Shibuya H,Yoshimura R,Miura M,Watanabe H,Kishimoto S,Omura K

更新日期：2013-05-01 00:00:00

abstract：CONCLUSION:Contrary to our expectation, that the clinical characteristics of temporal bone fracture would differ in children and adults, we found that the two groups were similar. OBJECTIVES:Most studies of temporal bone fractures have been performed in adults. To our knowledge, no study has investigated differences i...

journal_title：Acta oto-laryngologica

authors： Kang HM,Kim MG,Hong SM,Lee HY,Kim TH,Yeo SG

更新日期：2013-05-01 00:00:00